The C & H Refinery historic district is an intact industrial complex including the original house/office, refinery building and equipment, related storage tanks, and operation structures in their original locations. The refinery began petroleum distillation operations in 1933 and has recently been restored to operating conditions. In July 1999, the Guinness Book of World Records, Ltd. listed the C & H Refinery as the smallest functioning oil refinery in the world.

The Lusk Water Tower is significant for its association with the Chicago and North Western Rail Line (C&NW), a major railroad that stimulated Wyoming's settlement and development of rail transportation corridors. Massive water towers and windmills were regular features of station sites during the age of steam. The Lusk Water Tower was built by the Fremont, Elkhorn and Missouri Valley Railway (a subsidiary of C&NW) in 1886 when it extended its line from Chadron, Nebraska to Lusk, Douglas, and Casper, Wyoming. The redwood water tank is supported on timber piles; water was pumped from a well to the tank by windmill and then discharged into steam locomotives for boiler water. Originally, the water tower ws built in the center of Lusk near the depot. The water tower was moved to its location near the east boundary of the town of Lusk in 1919 when the depot was rebuilt. The Lusk Water Tower is Wyoming's only surviving railroad structure of its type.