The Izaak Walton League of America Charles E. Piersall Chapter Lodge is eligible for inclusion in the National Register of Historic Places as a locally significant building under Criterion A. The period of historical significance dates from 1934, when the building was constructed, to 1967. Significant dates include 1934, the year of construction, and 1953, the year of a major addition. The property is locally significant under Criterion A, as it is associated with events that have made a significant contribution to broad historical patterns in the conservation movement in Wyoming. It represents the local chapter of the national Izaak Walton League of America (IWL), a national organization dedicated to conservation. This building was constructed during the Great Depression with the aid of federal funding via New Deal programs to provide employment for Wyoming citizens.

The building is also eligible under Criterion C. It was designed by the prominent Casper architectural firm of Goodrich & Krusmark in the Rustic style and utilized locally available materials as much as possible. The Rustic architectural style common to Civilian Conservation Corps and Works Progress Association projects in the 1930s and the IWL. The other two National Register listed properties, in Nebraska and Indiana, were constructed in the Rustic style. The Rustic style is especially fitting for a building constructed for use by a conservation group. Local materials were employed in its construction: pine logs were cut and hauled from Casper Mountain and the stone used for the chimneys was quarried in nearby Jackson Canyon. The 1953 addition represents the evolution of the log aesthetic applied over time using new materials. The addition also represents the expansion of the conservationist movement in Wyoming during the mid-century period; simply put, the Casper chapter had outgrown the original Lodge.

Located on the plains west of Casper, the Stone Ranch Stage Station was constructed sometime around 1890. The stage station is a representative structure from a short era in Wyoming's transportation history when stage, freight and mail lines carried supplies and passengers from the terminus of a railway line to communities not yet serviced by a railroad. By the late 1880s the Wyoming Central Railroad had laid rails from Nebraska into Wyoming reaching Lusk, Douglas, Glenrock, and Casper. The movement of freight, supplies and passengers from the Casper terminus to Lander, however, depended upon privately owned and operated stage routes. The first stop on the route was at Stone Ranch. The station operated from 1897 to 1902 under the guidance of John (Jack) Clark as one of several stops operated by the Clark family. In 1902 the Utah-Nevada Express Company signed a four year contract to operate the stage line from Casper to Lander and Fort Washakie. Within six months this company failed and the U.S. Fidelity and Guaranty Company of Baltimore, bondsmen, took over the operation of the stage line. Steward and Joe Nails were sent to take charge and continued in that task until the railroad reached Lander in October 1906. The completion of the railway brought many new settlers to central Wyoming. Stock raising ventures prospered with the arrival of a reliable method of transporting sheep and cattle to markets. However, stage freight lines could not compete with railroads and routes adjacent to the railway line ceased to be corridors of commerce. Most of the stage stations closed including the station at Stone Ranch. The structure became part of the building complex at the ranch and served in many adaptive use capacities.